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10.1016/0014-5793(95)01050-O

Despite the well-established increase in IFP within breast tumors, our understanding of how breast cancer cells respond to this physical stimulus remains elusive due to the scarcity of reliable in vitro platforms that permit adjustment of pressure independent of changes in pH or the dissolved concentration of gases

Absolute contraindications include active malignancy, pregnancy, and lactation

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The peptide directly stimulates angiogenesis by promoting endothelial cell migration and proliferation while simultaneously modulating ERK1/2 signaling cascades that control cell growth, migration, and tissue remodeling