administer b12 injection Treating Severe Vitamin Deficiency How to self-inject intramuscular vitamin

Initial loading protocols often use daily or every-other-day dosing for the first one to two weeks, followed by weekly, then monthly maintenance

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Large doses of folic acid may also partially mask or worsen vitamin B deficiency by correcting anemia while allowing neurological damage to progress

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Subcutaneous B12 administration, although promising in select cases such as congenital cobalamin disorders, lacks comprehensive comparative studies against IM and oral routes