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In rats, both acute (4-h) and subchronic (7-day) cagrilintide treatment increased predicted Fos regulon activity in Glu4.2 Calcr/Ramp3 cells (adjusted P value ( P adj ) = 0.037 and P adj = 0.026, respectively

Ghosh, S., Valdecantos, P., Rada, P., Valverde, A

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10.1124/dmd.115.063107 49 ConradieF.BagdasaryanT

6 The practical takeaway for you: correcting a genuine selenium shortfall is worth doing, but piling extra selenium on top of an adequate intake isn't supported, and, as the next sections explain, it carries real risk