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Symptoms I Look For Brain (Neurological) Symptoms: Tremors or shaking Stiffness or abnormal postures (like dystonia) Trouble walking or using hands Slurred speech or difficulty swallowing Mood changes, forgetfulness, or confusion Liver Symptoms: Fatigue, weakness Yellow skin (jaundice) Swelling of belly Abnormal liver tests or early liver failure (especially in children) Eye Signs: Brownish ring in the cornea (Kayser-Fleischer ring) Found with an eye exam under slit-lamp A close-up of an eye with a visible Kayser-Fleischer ring, indicating copper accumulation in Wilsons Disease

An alternative treatment to xCT inhibition involves the depletion of its substrate, cystine

The overall life expectancy of the patient should be considered prior to screening for BO

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It is important to note that these early improvements are not universal